PostEra is building a modern, 21st-century biopharma. We use Proton, our AI
platform for medicinal chemistry, to accelerate the discovery of new medicines
for patients. PostEra is advancing an internal pipeline focused on Women's
Health and Reproductive Medicine while also advancing small-molecule programs
through partnerships with biopharma. We've closed over $1Bn in AI
partnerships, including four multi-year agreements with Pfizer and Amgen.
We've also been an active participant in open-science projects, leading a $68M
antiviral drug discovery center for pandemic preparedness, which followed on
from the success of COVID Moonshot, the world's largest open-science
initiative to develop a COVID antiviral.
PostEra's Organizational Structure:
· We believe time spent navigating complex hierarchies in organizations is
better invested in the pursuit of novel technology and scientific discoveries.
As such, our organizational structure is intentionally minimalist.
· We promote a culture where individual achievement is celebrated through
proportional compensation and internal recognition, including meaningful
promotions.
· Ultimately, our collective focus is delivering cures to patients, which we
believe needs a huge amount of cross-disciplinary collaboration, so we've
fitted our organizational structure to serve that end.
Role Overview:
In this role, you will be helping PostEra deliver on its mission of getting
therapies to patients by shaping systems design decisions around our drug
discovery platform, Proton. Design focus areas include things like data
architecture, microservice design, and patterns for running async compute-
heavy ML jobs.
In addition, you will keep close to the codebase by helping build and improve
the platform upon which our team delivers features. You will lead by example,
championing best practices in software development and engineering culture,
while also spearheading innovative projects that push the boundaries of drug
discovery.
You will make well thought out decisions about system architecture, including
API design, application boundaries, and microservice communication. These
systems should support the Proton platform in its pursuit to trivially handle
many concurrent drug discovery projects running in parallel at industry-
leading speed. Your leadership style should foster an environment of learning
and improvement within our engineering team in which you should strive to
build technical rapport with colleagues through coding and code review.
Key Responsibilities:
Technical Leadership and Execution: Lead the architectural design and
contribute to the development of scalable web applications and microservices.
Deep technical knowledge and professional experience:
· Using cloud providers (ideally AWS), container orchestration frameworks, and
IaC best practices.
· Working with teams who ship products using web-dev stacks composed of
Python, modern frontend frameworks, and relational databases like PostgreSQL.
Mentorship and Collaboration: Play a pivotal role in mentoring engineers,
promoting a culture of cross-team collaboration and continuous learning.
Candidate will:
· Be instrumental in facilitating knowledge sharing sessions, code reviews,
and defining team-wide technical standards.
· Nurture the technical growth of our team members, while directly managing a
small team of direct reports, with the possibility of growing into a larger
people leadership role.
Projects You May Lead:
Innovative Drug Discovery Projects: Collaborate with scientists and ML experts
to tackle challenges directly contributing to the discovery of novel
medicines. Specific challenges may include projects such as expanding
molecular search to 100B+ scale, designing automated AI-medicinal-chemist
workflows, bringing novel ML research to production, and creating tools for
real-time data analysis in drug design processes.
Engineering Excellence Initiatives: Drive projects focused on enhancing our
engineering framework such as architecting backend interactions with ML
systems, improving our CI/CD processes, setting new standards for code quality
and testing, incorporating AI tooling into our development processes, and
implementing monitoring solutions that offer real-time insights into our
applications' performance.
Key Requirements:
· 5+ years of experience and a bachelor's degree (or more advanced education)
to succeed in this role
· Experience in systems design and backend web development
· An interest in technical mentorship and management
Nice to Haves:
Candidate is more likely to succeed in this role if they also have:
· Expertise in a python based backend web framework (we use Django, for
example)
· Experience integrating ML systems into production services/software
· Familiarity with container orchestration or workflow systems (like:
Kubernetes, Kubeflow, Argo, Airflow)
· Have some familiarity with data pipelines
· Experience with designing agentic workflows/context engineering
· Past roles with technical mentorship focus or people management
responsibilities
Benefits
· PostEra offers comprehensive health, vision, and dental coverage as well as
life insurance
· 20 days PTO, unlimited sick leave
· 401K plans and up to 4% matching on contributions
· Generous budget for home office set up, co-working space, and weekly stipend
for lunch
· Quarterly in-person team gatherings, including three in Boston and one
company offsite annually
· Paid parental leave
Salary: 190k - 220k
Equity: 0.10% - 0.20%
Visa Sponsorship: Not at this time
Hiring Manager: Matt Robinson
Visit us at postera.ai